Dermatologist offers expert guidance on popular anti-aging treatments
Dermatologist Dr. Elizabeth Hale provides expert advice on the efficacy and safety of popular anti-aging treatments, from Botox to emerging trends like PDRN and Sculptra.
By Maya Morris ·

Dr. Elizabeth Hale, a prominent dermatologist, has provided detailed insights into the current landscape of cosmetic procedures. As a leading figure in the field, she addresses patient inquiries regarding a wide spectrum of interventions, ranging from standard botulinum toxin injections and laser therapies to emerging trends like peptides and salmon sperm facials. Her goal is to help individuals distinguish between effective methods that yield natural results and those that may be worth avoiding.
Botulinum toxin injections remain the most common minimally invasive cosmetic procedure in the United States, representing approximately half of all such treatments. Hale and her sister, who are both dermatologists, perform these injections daily at their practice, CompleteSkinMD. The mechanism involves selectively weakening facial muscles by inhibiting the release of acetylcholine, a neurotransmitter essential for muscle contraction. While the substance is derived from a toxic bacterium, Hale notes that it is quite safe and effective when administered by a licensed professional.
Many patients report that the effects of standard injections diminish over time. To maintain a natural appearance, Hale advises allowing for some movement in the treated areas as one ages. Beyond forehead lines, these injections are effective for crow's feet, frown lines, and crepey skin. They are also FDA approved for treating hyperhidrosis and migraines. The concept of baby Botox, which utilizes a smaller dosage, has gained popularity among younger demographics and celebrities seeking subtle softening of lines. However, Hale cautions that lower doses last shorter periods, requiring visits every one to two months. This increased frequency may lead to antibody formation, potentially reducing long-term efficacy.
For addressing crepey skin, which is often a sign of dehydration and sun damage, Hale emphasizes prevention through sun protection. She recommends a daily routine of moisturizing in the morning and applying retinol at night to aid cell turnover. For patients experiencing hormonal changes, topical estrogen therapies may help restore elasticity in delicate areas such as the neck. In more advanced cases, she suggests combining procedures like Fraxel laser resurfacing with fillers or microneedling to tighten collagen and improve texture.
Hale also discusses PDRN, an ingredient derived from salmon trout sperm that is widely used in Korea. While proponents claim it stimulates stem cells to rejuvenate skin, Hale has observed cases of granulomas or nodules in some patients due to foreign body reactions. Consequently, she recommends trying PDRN in the form of peels or topicals rather than injections. Regarding peptides, she acknowledges their theoretical benefit as building blocks of protein but notes that there is currently insufficient data to confirm their injectable efficacy. Similarly, while red light therapy can reduce inflammation and stimulate some collagen production, she does not view it as a cure-all for skin health.
Sculptra stands out as Hale's preferred procedure. This biostimulatory filler encourages the body's natural collagen production to gradually restore lost facial volume. Originally developed to treat facial wasting in patients with AIDS, the treatment has since become a staple in cosmetic dermatology. It is particularly beneficial for individuals who have experienced volume loss due to weight-loss medications or aging. Hale describes the results as gradual and slow, noting that the treatment significantly improves the quality of life for her patients.
Ultimately, Hale stresses that consistency is the most critical factor in maintaining healthy skin. She insists on a daily regimen of cleansing, moisturizing, and applying broad-spectrum sunscreen with an SPF of 30 or higher. She often declines to treat patients who are unwilling to commit to these foundational habits. According to her, looking young and healthy should not rely on quick fixes, but rather on the consistent care of the skin every day.
Source: CBS News
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